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Local false discovery rate facilitates comparison of different microarray experiments

The local false discovery rate (LFDR) estimates the probability of falsely identifying specific genes with changes in expression. In computer simulations, LFDR <10% successfully identified genes with changes in expression, while LFDR >90% identified genes without changes. We used LFDR to compa...

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Détails bibliographiques
Auteurs principaux: Hong, Wan-Jen, Tibshirani, Robert, Chu, Gilbert
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794175/
https://ncbi.nlm.nih.gov/pubmed/19825981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp813
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