Hedgehog inhibition reduces angiogenesis by downregulation of tumoral VEGF-A expression in hepatocellular carcinoma

BACKGROUND: Dysregulation and activation of Hedgehog (Hh) signalling may contribute to tumorigenesis, angiogenesis, and metastatic seeding in several solid tumours. OBJECTIVE: We investigated the impact of Hh inhibition on tumour growth and angiogenesis using in-vitro and in-vivo models of hepatocel...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Pinter, Matthias, Sieghart, Wolfgang, Schmid, Monika, Dauser, Bernhard, Prager, Gerald, Dienes, Hans Peter, Trauner, Michael, Peck-Radosavljevic, Markus
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2013
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040790/
https://ncbi.nlm.nih.gov/pubmed/24917971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640613496605
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker