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Control of glioma cell death and differentiation by PKM2–Oct4 interaction

Glioma stem cells are highly resistant to cell death and as such are supposed to contribute to tumor recurrence by eluding anticancer treatments. Here, we show that spheroids that contain rat neural stem cells (NSCs) or rat glioma stem cells (cancer stem cells, CSCs) express isoforms 1 and 2 of pyru...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Morfouace, M, Lalier, L, Oliver, L, Cheray, M, Pecqueur, C, Cartron, P-F, Vallette, F M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040711/
https://ncbi.nlm.nih.gov/pubmed/24481450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.561
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