Control of glioma cell death and differentiation by PKM2–Oct4 interaction

Glioma stem cells are highly resistant to cell death and as such are supposed to contribute to tumor recurrence by eluding anticancer treatments. Here, we show that spheroids that contain rat neural stem cells (NSCs) or rat glioma stem cells (cancer stem cells, CSCs) express isoforms 1 and 2 of pyru...

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Detalhes bibliográficos
Main Authors: Morfouace, M, Lalier, L, Oliver, L, Cheray, M, Pecqueur, C, Cartron, P-F, Vallette, F M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040711/
https://ncbi.nlm.nih.gov/pubmed/24481450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.561
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