Calcineurin suppresses AMPK-dependent cytoprotective autophagy in cardiomyocytes under oxidative stress

Calcineurin signalling plays a critical role in the pathogenesis of many cardiovascular diseases. Calcineurin has been proven to affect a series of signalling pathways and to exert a proapoptotic effect in cardiomyocytes. However, whether it is able to regulate autophagy remains largely unknown. Her...

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Hlavní autoři: He, H, Liu, X, Lv, L, Liang, H, Leng, B, Zhao, D, Zhang, Y, Du, Z, Chen, X, Li, S, Lu, Y, Shan, H
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040710/
https://ncbi.nlm.nih.gov/pubmed/24434520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.533
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