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c-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo

Altered synaptic function is considered one of the first features of Alzheimer disease (AD). Currently, no treatment is available to prevent the dysfunction of excitatory synapses in AD. Identification of the key modulators of synaptopathy is of particular significance in the treatment of AD. We her...

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Detalhes bibliográficos
Main Authors: Sclip, A, Tozzi, A, Abaza, A, Cardinetti, D, Colombo, I, Calabresi, P, Salmona, M, Welker, E, Borsello, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040696/
https://ncbi.nlm.nih.gov/pubmed/24457963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.559
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