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Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain

The glutamate-induced excitotoxicity pathway has been reported in several neurodegenerative diseases. Molecules that inhibit the release of glutamate or cause the overactivation of glutamate receptors can minimize neuronal cell death in these diseases. Osmotin, a homolog of mammalian adiponectin, is...

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Detalhes bibliográficos
Main Authors: Shah, S A, Lee, H Y, Bressan, R A, Yun, D J, Kim, M O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040667/
https://ncbi.nlm.nih.gov/pubmed/24481440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.538
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