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Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: A chemical chaperone at atomic resolution

Proteins are very sensitive to their solvent environments. Urea is a common chemical denaturant of proteins, yet some animals contain high concentrations of urea. These animals have evolved an interesting mechanism to counteract the effects of urea by using trimethylamine N-oxide (TMAO). The molecul...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Bennion, Brian J., Daggett, Valerie
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2004
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC404062/
https://ncbi.nlm.nih.gov/pubmed/15096583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308633101
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