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Membrane guanylyl cyclase complexes shape the photoresponses of retinal rods and cones

In vertebrate rods and cones, photon capture by rhodopsin leads to the destruction of cyclic GMP (cGMP) and the subsequent closure of cyclic nucleotide gated ion channels in the outer segment plasma membrane. Replenishment of cGMP and reopening of the channels limit the growth of the photon response...

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Bibliografiske detaljer
Main Authors: Wen, Xiao-Hong, Dizhoor, Alexander M, Makino, Clint L
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040495/
https://ncbi.nlm.nih.gov/pubmed/24917784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00045
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