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Changing genetic paradigms: creating next-generation genetic databases as tools to understand the emerging complexities of genotype/phenotype relationships

Understanding genotype/phenotype relationships has become more complicated as increasing amounts of inter- and intra-tissue genetic heterogeneity have been revealed through next-generation sequencing and evidence showing that factors such as epigenetic modifications, non-coding RNAs and RNA editing...

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Detalhes bibliográficos
Main Authors: Gottlieb, Bruce, Beitel, Lenore K, Trifiro, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040485/
https://ncbi.nlm.nih.gov/pubmed/24885908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-8-9
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