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Controversies in Cardiovascular Research: Role of Protein Kinase A Mediated Hyperphosphorylation of the Ryanodine Receptor at Serine 2808 in Heart Failure and Arrhythmias

This “Controversies in Research” article discusses the hypothesis that protein kinase A mediated phosphorylation of the Ryanodine Receptor (RyR) at a single serine (RyRS2808) is essential for normal sympathetic regulation of cardiac myocyte contractility and is responsible for the disturbed Ca(2+) r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Houser, Steven R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040460/
https://ncbi.nlm.nih.gov/pubmed/24723657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.300569
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