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The Chemokine Receptor D6 Constitutively Traffics to and from the Cell Surface to Internalize and Degrade Chemokines

The D6 heptahelical membrane protein, expressed by lymphatic endothelial cells, is able to bind with high affinity to multiple proinflammatory CC chemokines. However, this binding does not allow D6 to couple to the signaling pathways activated by typical chemokine receptors such as CC-chemokine rece...

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Autores principales: Weber, Michele, Blair, Emma, Simpson, Clare V., O'Hara, Maureen, Blackburn, Paul E., Rot, Antal, Graham, Gerard J., Nibbs, Robert J.B.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC404040/
https://ncbi.nlm.nih.gov/pubmed/15004236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-09-0634
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