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Brain-Derived Estrogen Exerts Anti-inflammatory and Neuroprotective Actions in the Rat Hippocampus

17β-estradiol (E2) has been implicated to play a critical role in neuroprotection, synaptic plasticity, and cognitive function. Classically, the role of gonadal-derived E2 in these events is well established, but the role of brain-derived E2 is less clear. To address this issue, we investigated the...

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Detalhes bibliográficos
Main Authors: Zhang, Quan-Guang, Wang, Ruimin, Tang, Hui, Dong, Yan, Chan, Alice, Sareddy, Gangadhara Reddy, Vadlamudi, Ratna K., Brann, Darrell W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040313/
https://ncbi.nlm.nih.gov/pubmed/24508637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2013.12.019
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