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SIRT1 in neurodevelopment and brain senescence
Sirtuins are nicotinamide adenine dinucleotide (NAD+)-dependent deacylases that have traditionally been linked with calorie restriction and aging in mammals. These proteins also play an important role in maintaining neuronal health during aging. During neuronal development, the SIR2 ortholog SIRT1 i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040287/ https://ncbi.nlm.nih.gov/pubmed/24507186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.01.028 |
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