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The Role of Valvular Endothelial Cell Paracrine Signaling and Matrix Elasticity on Valvular Interstitial Cell Activation

The effects of valvular endothelial cell (VlvEC) paracrine signaling on VIC phenotype and nodule formation were tested using a co-culture platform with physiologically relevant matrix elasticities and diffusion distance. 100μm thin poly(ethylene glycol) (PEG) hydrogels of 3 to 27 kPa Young’s moduli...

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Autors principals: Gould, Sarah T., Matherly, Emily E., Smith, Jennifer N., Heistad, Donald D., Anseth, Kristi S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040249/
https://ncbi.nlm.nih.gov/pubmed/24462357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.01.005
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