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Plant extracts inhibit ADP-induced platelet activation in humans: their potential therapeutic role as ADP antagonists

Adenosine diphosphate (ADP) plays a pivotal role in platelet activation. Platelet hyperactivity is associated with vascular disease and also has a key role in haemostasis and thrombosis. ADP activates platelets through three purinoceptor subtypes, the G(q)-coupled P2Y(1) receptor, G(i)-coupled P2Y(1...

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Detalhes bibliográficos
Autor principal: Jagroop, Indera Anita
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040171/
https://ncbi.nlm.nih.gov/pubmed/24190032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-013-9393-0
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