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Creatine kinase inhibits ADP-induced platelet aggregation

Bleeding risk with antiplatelet therapy is an increasing clinical challenge. However, the inter-individual variation in this risk is poorly understood. We assessed whether the level of plasma creatine kinase, the enzyme that utilizes ADP and phosphocreatine to rapidly regenerate ATP, may modulate bl...

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Autores principales: Horjus, D. L., Nieuwland, R., Boateng, K. B., Schaap, M. C. L., van Montfrans, G. A., Clark, J. F., Sturk, A., Brewster, L. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190537/
https://ncbi.nlm.nih.gov/pubmed/25298190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06551
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