Creatine kinase inhibits ADP-induced platelet aggregation

Bleeding risk with antiplatelet therapy is an increasing clinical challenge. However, the inter-individual variation in this risk is poorly understood. We assessed whether the level of plasma creatine kinase, the enzyme that utilizes ADP and phosphocreatine to rapidly regenerate ATP, may modulate bl...

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Main Authors: Horjus, D. L., Nieuwland, R., Boateng, K. B., Schaap, M. C. L., van Montfrans, G. A., Clark, J. F., Sturk, A., Brewster, L. M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190537/
https://ncbi.nlm.nih.gov/pubmed/25298190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06551
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