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Dominant Gain-of-Function Mutations in Hsp104p Reveal Crucial Roles for the Middle Region

Heat-shock protein 104 (Hsp104p) is a protein-remodeling factor that promotes survival after extreme stress by disassembling aggregated proteins and can either promote or prevent the propagation of prions (protein-based genetic elements). Hsp104p can be greatly overexpressed without slowing growth,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schirmer, Eric C., Homann, Oliver R., Kowal, Anthony S., Lindquist, Susan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC404004/
https://ncbi.nlm.nih.gov/pubmed/14978213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-08-0502
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