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Dominant Gain-of-Function Mutations in Hsp104p Reveal Crucial Roles for the Middle Region
Heat-shock protein 104 (Hsp104p) is a protein-remodeling factor that promotes survival after extreme stress by disassembling aggregated proteins and can either promote or prevent the propagation of prions (protein-based genetic elements). Hsp104p can be greatly overexpressed without slowing growth,...
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| Veröffentlicht in: | Mol Biol Cell |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Cell Biology
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC404004/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14978213/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-08-0502 |
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