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Immune escape from NY-ESO-1-specific T cell therapy via loss of heterozygosity in the MHC

Adoptive immunotherapy of tumors with T cells specific for the cancer-testis antigen NY-ESO-1 has shown great promise in preclinical models and in early stage clinical trials. Tumor persistence or recurrence after NY-ESO-1-specific therapy occurs, however, and the mechanisms of recurrence remain poo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Klippel, Zandra K., Chou, Jeffrey, Towlerton, Andrea M., Voong, Lilien N., Robbins, Paul, Bensinger, William I., Warren, Edus H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040020/
https://ncbi.nlm.nih.gov/pubmed/24451117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.87
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