Effects of o-vanillin on K(+) transport of red blood cells from patients with sickle cell disease

Aromatic aldehydes like o-vanillin were designed to reduce the complications of sickle cell disease (SCD) by interaction with HbS, to reduce polymerisation and RBC sickling. Present results show that o-vanillin also directly affects RBC membrane permeability. Both the K(+)–Cl(−) cotransporter (KCC)...

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Detalhes bibliográficos
Main Authors: Hannemann, A., Cytlak, U.M.C., Gbotosho, O.T., Rees, D.C., Tewari, S., Gibson, J.S.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039999/
https://ncbi.nlm.nih.gov/pubmed/24594314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2014.02.004
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