Cytokine responsiveness of CD8(+) T cells is a reproducible biomarker for the clinical efficacy of dendritic cell vaccination in glioblastoma patients

BACKGROUND: Immunotherapeutic approaches, such as dendritic cell (DC) vaccination, have emerged as promising strategies in the treatment of glioblastoma. Despite their promise, however, the absence of objective biomarkers and/or immunological monitoring techniques to assess the clinical efficacy of...

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Main Authors: Everson, Richard G, Jin, Richard M, Wang, Xiaoyan, Safaee, Michael, Scharnweber, Rudi, Lisiero, Dominique N, Soto, Horacio, Liau, Linda M, Prins, Robert M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039989/
https://ncbi.nlm.nih.gov/pubmed/24883189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-1426-2-10
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