RhoGDI2 promotes epithelial-mesenchymal transition via induction of Snail in gastric cancer cells

Rho GDP dissociation inhibitor 2 (RhoGDI2) expression correlates with tumor growth, metastasis, and chemoresistance in gastric cancer. Here, we show that RhoGDI2 functions in the epithelial-mesenchymal transition (EMT), which is responsible for invasiveness during tumor progression. This tumorigenic...

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Hauptverfasser: Cho, Hee Jun, Park, Sun-Mi, Kim, In-Kyu, Nam, In-Koo, Baek, Kyoung Eun, Im, Min-Ju, Yoo, Jong-Min, Park, Seung-Ho, Ryu, Ki-Jun, Han, Hyun-Tak, Kim, Hyo-Jin, Hong, Soon-Chan, Kim, Kwang Dong, Pak, Yunbae, Kim, Jae Won, Lee, Chang Won, Yoo, Jiyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039231/
https://ncbi.nlm.nih.gov/pubmed/24721928
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