Caspase-3 and Caspase-6 cleave STAT1 in leukemic cells

Signal Transducer and Activator of Transcription-1 (STAT1) is phosphorylated upon interferon (IFN) stimulation, which can restrict cell proliferation and survival. Nevertheless, in some cancers STAT1 can act in an anti-apoptotic manner. Moreover, certain malignancies are characterized by the overexp...

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Autores principales: Licht, Verena, Noack, Katrin, Schlott, Bernhard, Förster, Martin, Schlenker, Yvonne, Licht, Andreas, Krämer, Oliver H., Heinzel, Thorsten
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039164/
https://ncbi.nlm.nih.gov/pubmed/24810717
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