Polyubiquitylation of AMF requires cooperation between the gp78 and TRIM25 ubiquitin ligases

gp78 is a ubiquitin ligase that plays a vital role in endoplasmic reticulum (ER)-associated degradation (ERAD). Here we report that autocrine motility factor (AMF), also known as phosphoglucose isomerase (PGI), is a novel substrate of gp78. We show that polyubiquitylation of AMF requires cooperative...

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Detalhes bibliográficos
Main Authors: Wang, Ying, Ha, Seung-Wook, Zhang, Tianpeng, Kho, Dhong-Hyo, Raz, Avraham, Xie, Youming
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039143/
https://ncbi.nlm.nih.gov/pubmed/24810856
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