Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another “double hit” lymphoma with very poor outcome?

MiR34A, B and C have been implicated in lymphomagenesis, but information on their role in normal CD19+ B-cells (PBL-B) and de novo diffuse large B-cell lymphoma (DLBCL) is limited. We show that in normal and activated B-cells miR34A-5p plays a dominant role compared to other miR34 family members. On...

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Détails bibliographiques
Auteurs principaux: Asmar, Fazila, Hother, Christoffer, Kulosman, Gorjan, Treppendahl, Marianne Bach, Nielsen, Helene Myrtue, Ralfkiaer, Ulrik, Pedersen, Anja, Møller, Michael Boe, Ralfkiaer, Elisabeth, de Nully Brown, Peter, Grønbæk, Kirsten
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2014
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039115/
https://ncbi.nlm.nih.gov/pubmed/24722400
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