Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma

The discovery that the Ten-Eleven Translocation (TET) hydroxylases cause DNA demethylation has fundamentally changed the notion of how DNA methylation is regulated. Clonal analysis of the hematopoetic stem cell compartment suggests that TET2 mutations can be early events in hematologic cancers and r...

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Autors principals: Asmar, Fazila, Punj, Vasu, Christensen, Jesper, Pedersen, Marianne T., Pedersen, Anja, Nielsen, Anders B., Hother, Christoffer, Ralfkiaer, Ulrik, Brown, Peter, Ralfkiaer, Elisabeth, Helin, Kristian, Grønbæk, Kirsten
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856967/
https://ncbi.nlm.nih.gov/pubmed/23831920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.088740
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