Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma

The discovery that the Ten-Eleven Translocation (TET) hydroxylases cause DNA demethylation has fundamentally changed the notion of how DNA methylation is regulated. Clonal analysis of the hematopoetic stem cell compartment suggests that TET2 mutations can be early events in hematologic cancers and r...

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Main Authors: Asmar, Fazila, Punj, Vasu, Christensen, Jesper, Pedersen, Marianne T., Pedersen, Anja, Nielsen, Anders B., Hother, Christoffer, Ralfkiaer, Ulrik, Brown, Peter, Ralfkiaer, Elisabeth, Helin, Kristian, Grønbæk, Kirsten
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856967/
https://ncbi.nlm.nih.gov/pubmed/23831920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.088740
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