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The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of upper and lower motor neurons. Although the etiology remains unclear, disturbances in calcium homoeostasis and protein folding are essential features of neurodegeneration in this disorder. Here, w...

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Bibliografische gegevens
Hoofdauteurs: Tadic, Vedrana, Prell, Tino, Lautenschlaeger, Janin, Grosskreutz, Julian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039088/
https://ncbi.nlm.nih.gov/pubmed/24910594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00147
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