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The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of upper and lower motor neurons. Although the etiology remains unclear, disturbances in calcium homoeostasis and protein folding are essential features of neurodegeneration in this disorder. Here, w...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4039088/ https://ncbi.nlm.nih.gov/pubmed/24910594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00147 |
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