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Pinpointing brainstem mechanisms responsible for autonomic dysfunction in Rett syndrome: therapeutic perspectives for 5-HT(1A) agonists

Rett syndrome is a neurological disorder caused by loss of function of methyl-CpG-binding protein 2 (MeCP2). Reduced function of this ubiquitous transcriptional regulator has a devastating effect on the central nervous system. One of the most severe and life-threatening presentations of this syndrom...

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Detalhes bibliográficos
Main Authors: Abdala, Ana P., Bissonnette, John M., Newman-Tancredi, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038922/
https://ncbi.nlm.nih.gov/pubmed/24910619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00205
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