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The Impact of Population Demography and Selection on the Genetic Architecture of Complex Traits

Population genetic studies have found evidence for dramatic population growth in recent human history. It is unclear how this recent population growth, combined with the effects of negative natural selection, has affected patterns of deleterious variation, as well as the number, frequency, and effec...

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Bibliographic Details
Main Author: Lohmueller, Kirk E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038606/
https://ncbi.nlm.nih.gov/pubmed/24875776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004379
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