The Inflammasome Pyrin Contributes to Pertussis Toxin-Induced IL-1β Synthesis, Neutrophil Intravascular Crawling and Autoimmune Encephalomyelitis

Microbial agents can aggravate inflammatory diseases, such as multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). An example is pertussis toxin (PTX), a bacterial virulence factor commonly used as an adjuvant to promote EAE, but whose mechanism of action is...

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Detalhes bibliográficos
Main Authors: Dumas, Aline, Amiable, Nathalie, de Rivero Vaccari, Juan Pablo, Chae, Jae Jin, Keane, Robert W., Lacroix, Steve, Vallières, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038594/
https://ncbi.nlm.nih.gov/pubmed/24875775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004150
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