The Inflammasome Pyrin Contributes to Pertussis Toxin-Induced IL-1β Synthesis, Neutrophil Intravascular Crawling and Autoimmune Encephalomyelitis

Microbial agents can aggravate inflammatory diseases, such as multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). An example is pertussis toxin (PTX), a bacterial virulence factor commonly used as an adjuvant to promote EAE, but whose mechanism of action is...

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Bibliografische gegevens
Hoofdauteurs: Dumas, Aline, Amiable, Nathalie, de Rivero Vaccari, Juan Pablo, Chae, Jae Jin, Keane, Robert W., Lacroix, Steve, Vallières, Luc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038594/
https://ncbi.nlm.nih.gov/pubmed/24875775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004150
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