ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R–mediated apoptosis

Myeloid-derived suppressor cells (MDSCs) dampen the immune response thorough inhibition of T cell activation and proliferation and often are expanded in pathological conditions. Here, we studied the fate of MDSCs in cancer. Unexpectedly, MDSCs had lower viability and a shorter half-life in tumor-bea...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Condamine, Thomas, Kumar, Vinit, Ramachandran, Indu R., Youn, Je-In, Celis, Esteban, Finnberg, Niklas, El-Deiry, Wafik S., Winograd, Rafael, Vonderheide, Robert H., English, Nickolas R., Knight, Stella C., Yagita, Hideo, McCaffrey, Judith C., Antonia, Scott, Hockstein, Neil, Witt, Robert, Masters, Gregory, Bauer, Thomas, Gabrilovich, Dmitry I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038578/
https://ncbi.nlm.nih.gov/pubmed/24789911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74056
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados