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Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts

Female mice lacking protein tyrosine phosphatase ε (PTP ε) are mildly osteopetrotic. Osteoclasts from these mice resorb bone matrix poorly, and the structure, stability, and cellular organization of their podosomal adhesion structures are abnormal. Here we compare the role of PTP ε with that of the...

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Hlavní autoři: Finkelshtein, Eynat, Lotinun, Sutada, Levy-Apter, Einat, Arman, Esther, den Hertog, Jeroen, Baron, Roland, Elson, Ari
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038506/
https://ncbi.nlm.nih.gov/pubmed/24694598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-03-0788
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