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Inferring Host Gene Subnetworks Involved in Viral Replication
Systematic, genome-wide loss-of-function experiments can be used to identify host factors that directly or indirectly facilitate or inhibit the replication of a virus in a host cell. We present an approach that combines an integer linear program and a diffusion kernel method to infer the pathways th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4038467/ https://ncbi.nlm.nih.gov/pubmed/24874113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003626 |
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