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Inferring Host Gene Subnetworks Involved in Viral Replication

Systematic, genome-wide loss-of-function experiments can be used to identify host factors that directly or indirectly facilitate or inhibit the replication of a virus in a host cell. We present an approach that combines an integer linear program and a diffusion kernel method to infer the pathways th...

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Detaylı Bibliyografya
Asıl Yazarlar: Chasman, Deborah, Gancarz, Brandi, Hao, Linhui, Ferris, Michael, Ahlquist, Paul, Craven, Mark
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038467/
https://ncbi.nlm.nih.gov/pubmed/24874113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003626
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