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Reinitiation and other unconventional post-termination events during eukaryotic translation

During ribosome recycling, post-termination complexes are dissociated by ABCE1 and eRF1 into 60S and tRNA/mRNA-associated 40S subunits, after which tRNA/mRNA are released by eIF1/eIF1A, Ligatin or MCT1/DENR. In some instances, 40S subunits remain associated with mRNA and reinitiate at nearby AUGs. H...

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Hauptverfasser: Skabkin, Maxim A., Skabkina, Olga V., Hellen, Christopher U. T., Pestova, Tatyana V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038429/
https://ncbi.nlm.nih.gov/pubmed/23810859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.05.026
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