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λ-prophage induction modeled as a cooperative failure mode of lytic repression

We analyze a system-level model for lytic repression of λ-phage in E. coli using reliability theory, showing that the repressor circuit comprises 4 redundant components whose failure mode is prophage induction. Our model reflects the specific biochemical mechanisms involved in regulation, including...

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Detaylı Bibliyografya
Asıl Yazarlar: Chia, Nicholas, Golding, Ido, Goldenfeld, Nigel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038166/
https://ncbi.nlm.nih.gov/pubmed/19905052
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