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Suppression of interactions between prostate tumor cell integrin α(v)β(3) and endothelial ICAM-1 by simvastatin inhibits prostate cancer micrometastasis

Cancer micrometastasis relies on the ability of cancer cells to secrete angiogenic modulators, to interact with the vascular endothelium, and to overcome the resistance offered by the endothelial-barrier. Being an essential step prior to metastasis, blockage of micrometastasis can have potential app...

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Autori principali: Al-Husein, Belal, Goc, Anna, Somanath, Payaningal R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038100/
https://ncbi.nlm.nih.gov/pubmed/23559257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24381
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