Autoimmune Kidney Disease and Impaired Engulfment of Apoptotic Cells in Mice with Macrophage Peroxisome Proliferator-Activated Receptor γ or Retinoid X Receptor α Deficiency

Autoimmune glomerulonephritis is a common manifestation of systemic lupus erythematosus (SLE). In this study, we show that mice lacking macrophage expression of the heterodimeric nuclear receptors PPARγ or RXRα develop glomerulonephritis and autoantibodies to nuclear Ags, resembling the nephritis se...

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Detaylı Bibliyografya
Asıl Yazarlar: Rőszer, Tamás, Menéndez-Gutiérrez, María P., Lefterova, Martina I., Alameda, Daniel, Núñez, Vanessa, Lazar, Mitchell A., Fischer, Thierry, Ricote, Mercedes
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038038/
https://ncbi.nlm.nih.gov/pubmed/21135166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002230
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