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Inflammatory Mediators and Insulin Resistance in Obesity: Role of Nuclear Receptor Signaling in Macrophages
Visceral obesity is coupled to a general low-grade chronic inflammatory state characterized by macrophage activation and inflammatory cytokine production, leading to insulin resistance (IR). The balance between proinflammatory M1 and antiinflammatory M2 macrophage phenotypes within visceral adipose...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Hindawi Publishing Corporation
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874923/ https://ncbi.nlm.nih.gov/pubmed/20508742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/219583 |
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