Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer

Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-react with endogenous molecules. Scleroderma is an autoimmune connective tissue disease in which patients make antibodies to a limited group of autoantigens, including RPC1, encoded by the POLR3A gene. As pat...

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Main Authors: Joseph, Christine G., Darrah, Erika, Shah, Ami A., Skora, Andrew D., Casciola-Rosen, Livia A., Wigley, Fredrick M., Boin, Francesco, Fava, Andrea, Thoburn, Chris, Kinde, Isaac, Jiao, Yuchen, Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Rosen, Antony
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038033/
https://ncbi.nlm.nih.gov/pubmed/24310608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1246886
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