Purinergic Autocrine Regulation of Mechanosensitivity and Serotonin Release in a Human EC Model: ATP-gated P2X(3) Channels in EC are Downregulated in Ulcerative Colitis

BACKGROUND: Alterations in 5-hydroxytryptamine (HT) signaling in inflamed gut may contribute to pathogenesis of inflammatory bowel diseases. Adenosine 5′-triphosphate (ATP) regulates mucosal-mechanosensory reflexes and ATP receptors are sensitive to mucosal inflammation. Yet, it remains unknown whet...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Liñán-Rico, Andrómeda, Wunderlich, Jacqueline E., Grants, Iveta S., Frankel, Wendy L., Xue, Jianjing, Williams, Kent C., Harzman, Alan E., Enneking, Joshua T., Cooke, Helen J., Christofi, Fievos L.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037929/
https://ncbi.nlm.nih.gov/pubmed/23917247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e31829ecf4d
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars