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Estimation of Gene-Environment Interaction by Pooling Biospecimens
Case-control studies are prone to low power for testing gene-environment interactions (GXE) given the need for a sufficient number of individuals on each strata of disease, gene, and environment. We propose a new study design to increase power by strategically pooling biospecimens. Pooling biospecim...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4037867/ https://ncbi.nlm.nih.gov/pubmed/22859290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5357 |
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