Coexistence of EGFR with KRAS, or BRAF, or PIK3CA somatic mutations in lung cancer: a comprehensive mutation profiling from 5125 Chinese cohorts

BACKGROUND: Determining the somatic mutations of epidermal growth factor receptor (EGFR)-pathway networks is the key to effective treatment for non-small cell lung cancer (NSCLC) with tyrosine kinase inhibitors (TKIs).The somatic mutation frequencies and their association with gender, smoking histor...

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Detalhes bibliográficos
Main Authors: Li, S, Li, L, Zhu, Y, Huang, C, Qin, Y, Liu, H, Ren-Heidenreich, L, Shi, B, Ren, H, Chu, X, Kang, J, Wang, W, Xu, J, Tang, K, Yang, H, Zheng, Y, He, J, Yu, G, Liang, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037826/
https://ncbi.nlm.nih.gov/pubmed/24743704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.210
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