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ATF4- and CHOP-Dependent Induction of FGF21 through Endoplasmic Reticulum Stress

Fibroblast growth factor 21 (FGF21) is an important endogenous regulator involved in the regulation of glucose and lipid metabolism. FGF21 expression is strongly induced in animal and human subjects with metabolic diseases, but little is known about the molecular mechanism. Endoplasmic reticulum (ER...

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Bibliografske podrobnosti
Main Authors: Wan, Xiao-shan, Lu, Xiang-hong, Xiao, Ye-cheng, Lin, Yuan, Zhu, Hong, Ding, Ting, Yang, Ying, Huang, Yan, Zhang, Yi, Liu, Yan-Long, Xu, Zhu-mei, Xiao, Jian, Li, Xiao-kun
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037570/
https://ncbi.nlm.nih.gov/pubmed/24900988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/807874
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