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In vitro generation of colonic epithelium from primary cells guided by microstructures

The proliferative compartment of the colonic epithelium in vivo is located in the basal crypt where colonic stem cells and transit-amplifying cells reside and fuel the rapid renewal of non-proliferative epithelial cells as they migrate toward the gut lumen. To mimic this tissue polarity, microstruct...

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Autors principals: Wang, Yuli, Ahmad, Asad A., Sims, Christopher E., Magness, Scott T., Allbritton, Nancy L.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037563/
https://ncbi.nlm.nih.gov/pubmed/24647645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3lc51353j
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