Quantitative measurements of HER2 and phospho-HER2 expression: correlation with pathologic response to neoadjuvant chemotherapy and trastuzumab

BACKGROUND: Preoperative therapy with chemotherapy and the HER2-targeted monoclonal antibody trastuzumab is valuable for patients with large or locally advanced HER2-positive (HER2+) breast cancers but traditional methods of measuring HER2 expression do not accurately stratify patients for likelihoo...

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Autors principals: Cheng, Huan, Bai, Yalai, Sikov, William, Sinclair, Natalie, Bossuyt, Veerle, Abu-Khalaf, Maysa M, Harris, Lyndsay N, Rimm, David L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037428/
https://ncbi.nlm.nih.gov/pubmed/24885187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-326
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