Reductions in Brain 5-HT(1B) Receptor Availability in Primarily Cocaine-Dependent Humans

BACKGROUND: Preclinical evidence implicates the 5-HT(1B) receptor in cocaine’s effects. This study explores 5-HT(1B) in humans by examining receptor availability in vivo with primary cocaine-dependent (CD) subjects using positron emission tomography (PET). METHODS: Fourteen medically healthy CD subj...

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Détails bibliographiques
Auteurs principaux: Matuskey, David, Bhagwagar, Zubin, Planeta, Beata, Pittman, Brian, Gallezot, Jean-Dominique, Chen, Jason, Wanyiri, Jane, Najafzadeh, Soheila, Ropchan, Jim, Geha, Paul, Huang, Yiyun, Potenza, Marc N., Neumeister, Alexander, Carson, Richard E., Malison, Robert T.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037398/
https://ncbi.nlm.nih.gov/pubmed/24433854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.11.022
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