β-Adrenergic Receptor-Mediated Transactivation Of Epidermal Growth Factor Receptor Decreases Cardiomyocyte Apoptosis Through Differential Subcellular Activation of ERK1/2 and Akt

RATIONALE: β-adrenergic receptor (βAR)-mediated transactivation of epidermal growth factor receptor (EGFR) has been shown to relay pro-survival effects via unknown mechanisms. OBJECTIVE: We hypothesized that acute βAR-mediated EGFR transactivation in the heart promotes differential subcellular activ...

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Autors principals: Grisanti, Laurel A., Talarico, Jennifer A., Carter, Rhonda L., Yu, Justine E., Repas, Ashley A., Radcliffe, Scott W., Tang, Hoang-ai, Makarewich, Catherine A., Houser, Steven R., Tilley, Douglas G.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037368/
https://ncbi.nlm.nih.gov/pubmed/24566221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.02.009
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