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Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genomewide Association Study

PURPOSE: Identification of single nucleotide polymorphisms (SNPs) associated with development of advanced colorectal adenomas. EXPERIMENTAL DESIGN: Discovery Phase: 1,406 Caucasian patients (139 advanced adenoma cases and 1,267 controls) from the Adenoma Prevention with Celecoxib (APC) trial were in...

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Detalhes bibliográficos
Main Authors: Wang, Jiping, Carvajal-Carmona, Luis G., Chu, Jen-Hwa, Zauber, Ann G., Kubo, Michikai, Matsuda, Koichi, Dunlop, Malcolm, Houlston, Richard S., Sieber, Oliver, Lipton, Lara, Gibbs, Peter, Martin, Nicholas G., Montgomery, Grant W., Young, Joanne, Baird, Paul N., Ratain, Mark J., Nakamura, Yusuke, Weiss, Scott T., Tomlinson, Ian, Bertagnolli, Monica M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037290/
https://ncbi.nlm.nih.gov/pubmed/24084763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0550
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